Toxicology and Carcinogenesis Studies of Sodium Chlorate in F344/N Rats and B6C3F1 Mice

Sodium chlorate is used as an oxidizing agent & bleach for paper pulp; to make chlorine dioxide used in water disinfection; in ore processing; in the manufacture of matches & explosives; in dye making & the printing & dyeing of fabrics; in leather finishing & tanning; to make perchlorates; in toothpaste & mouthwash; & as a non-selective herbicide, defoliant, & harvest aid. Chlorate is found as a stable byproduct in drinking water that has been disinfected with chlorine dioxide. Sodium chlorate is being studied because of widespread consumer exposure to treated drinking water & lack of carcinogenicity data. Genetic toxicology studies were conducted in Salmonella typhimurium & mouse peripheral blood erythrocytes. Tables & illustrations.Hooth, M. J. is the author of 'Toxicology and Carcinogenesis Studies of Sodium Chlorate in F344/N Rats and B6C3F1 Mice', published 2006 under ISBN 9781422306123 and ISBN 1422306127.