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9780192623713

The NMDA Receptor - Graham L. Collingridge - Hardcover - REV

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  • ISBN-13: 9780192623713
  • ISBN: 0192623710
  • Edition: 2
  • Publisher: Oxford University Press, Incorporated

AUTHOR

Collingridge, Graham L., Watkins, Jeffrey C.

SUMMARY

1. The NMDA receptor concept: origins and development 2. Agonists and competitive antagonists: structure, activity and molecular modelling studies 3. Non-competitive antagonists of N-methyl-D-aspartate 4. Molecular pharmacology of NMDA receptors 5. Molecular biology of NMDA receptors 6. Anatomical, pharmacological, and molecular diversity of native NMDA receptor subtypes 7. The NMDA receptor, its channel, and its modulation by glycine 8. The time-course of NMDA receptor-mediated synaptic currents 9. Activation of NMDA receptors 10. NMDA receptors and their interactions with other excitatory amino acid receptors in synaptic transmission in the mammalian central nervous system 11. The importance of NMDA receptors in the processing of spinal primary afferent input patterns 12. The role of NMDA receptors in synaptic integration and the organization of motor patterns 13. NMDA receptors and long-term potentiation in the hippocampus 14. NMDA receptors and developmental plasticity in visual neocortex 15. The role of NMDA receptors in learning and memory 16. Clinical implications of NMDA receptors 17. The NMDA receptor in epilepsy 18. NMDA receptors, neuronal development, and neurodegeneration 19. Competitive NMDA antagonists as drugs 20. Non-competitive NMDA antagonists as drugsCollingridge, Graham L. is the author of 'The NMDA Receptor - Graham L. Collingridge - Hardcover - REV' with ISBN 9780192623713 and ISBN 0192623710.

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