Intracellular Protein Degradation: In Focus

Intracellular protein degradation is becoming an area of widely increasing research. It is central to both normal cellular homeostasis and chronic degenerative and viral diseases. Many of the currently incompletely understood human diseases are in fact protein catabolic disorders of some sort. This important book describes the mechanisms of intracellular protein degradation at the molecular and cell biological levels. Topics include the kinetics of protein degradation, lysosomes, cystosolic proteases, the ubiquitin pathway, molecular determinants of protein half-line, and protein degradation in disease. The book will be invaluable to researchers and students in biochemistry, cell biology, and medicine.Doherty, Fergus J. is the author of 'Intracellular Protein Degradation: In Focus' with ISBN 9780199632930 and ISBN 0199632936.