25962677
9781422315200
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Dichloroacetic acid was nominated for study by the EPA because of its widespread occurrence in drinking water as a byproduct of water disinfection using chlorination. It was also nominated because dicholoroacetic acid is the most studied representative of the class of haloacetic acids & has been shown to cause liver tumors in both rats & mice. Haloacetic acids are second only to trihalomethanes as a family of disinfection byproducts found in many drinking water supplies. Dichloroacetic acid is one of several disinfection byproducts being evaluated to determine whether genetically modified mouse models can serve as a more rapid & cost-effective means of evaluating & ranking potential hazards of disinfection byproducts. Illustrations.Boorman, G. A. is the author of 'Genetically Modified Model Report on Toxicology and Carcinogeneticity Studies of Dichloroacetic Acid (CAS No. 79-43-6) in Genetically Modified (FVB Tb. ACV Hemizygous) Mice (Dermal and Drinking Water Studies) and Carcinogenecity Studies of Dichloroacetic ', published 2007 under ISBN 9781422315200 and ISBN 1422315207.
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