By examining human drug use from historical, societal, and biological perspectives, Grilly, Drugs and Human Behavior, Fifth Edition, provides a rich foundation for understanding drugs affecting the brain. In addition to describing basic pharmacological principles, this text discusses the general factors behind drug tolerance, dependence, and abuse and approaches for dealing with these problems. Pharmacotherapy for the major mental disorders is described from both biochemical and clinical efficacy perspectives. By using the most up-to-date research, and by presenting data in concise, jargon-free prose, the author has created one of the most comprehensive and accessible books on the subject. Book jacket.Grilly, David M. is the author of 'Drugs and Human Behavior' with ISBN 9780205118687 and ISBN 0205118682.