Development of Sustainable Bioprocesses Modeling and Assessment

This book provides a framework for the development of sustainable bioprocesses. It includes methods for modeling and assessing both the economic and environmental aspects of biotechnological processes and illustrates their application in a series of case studies covering a broad range of products. The book: provides, in four chapters, an introduction to bioproducts and bioprocesses and the unit operations involved in manufacturing, as well as bioprocess modeling in combination with economic and environmental assessment methods; cuts across multiple process industries, including pharmaceutical, biochemicals, chemicals and food production; addresses risk and uncertainty analysis which are particularly important in early process and product development; presents a unique set of case examples from various parts of biotechnology that improve the understanding of this technology and provide a starting point for developing a specific model. The CD-ROM included contains the process models described in the text. All process model examples are implemented into SuperPro Designer . The models are selected as characteristic examples of major bioprocess applications including bulk bio-chemicals, fine chemicals, enzymes, low and high molecular weight pharmaceuticals. Topics covered are: Citric Acid, Pyruvic Acid, L-Lysine, Riboflavin - Vitamin B2, -Cyclodextrin, Penicillin V, Recombinant Human Serum Albumin, Recombinant Human Insulin; Monoclonal Antibodies, -1-Antitrypsin from Transgenic Plant Cell Suspension Cultures and Plasmid DNA production. These examples provide a hands-on-approach, which will be useful to both students and professionals already working in bioprocess industries. This book provides an integrating framework for the student in chemical and biochemical engineering and the scientist and engineer engaged in process development working in the biochemical, chemical and process industries, as well as biologists, chemists, environmental managers and business economists. The authors acknowledge the sponsorship of the Deutsche Bundesstiftung Umwelt, Osnabr ck, Germany.Heinzle, Elmar is the author of 'Development of Sustainable Bioprocesses Modeling and Assessment', published 2007 under ISBN 9780470015599 and ISBN 0470015594.