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Publication Date: 2006
Publisher: DIANE Publishing Company
Bernheim, N. J.
In the past 20 years, the Nat. Toxicology Program (NTP) has primarily used rodents in studies to determine the potential carcinogenic hazard from chemicals that occur in the workplace or environment. Because rodent cancer studies are costly & require years to complete, the NTP continues to investigate other animal models that may offer advantages in terms of time, cost, & mechanistic information. Several small fish species have been suggested. To examine fish as a test species for cancer hazard identification, the NTP decided to evaluate two small fish models using 3 chemicals under standard study conditions. This report details the experience with the medaka & guppy for 3 rodent carcinogens. Charts & tables.Bernheim, N. J. is the author of 'Carcinogenesis Studies of 2,2-Bis -1,3-Propanediol Nitromethane, And 1,2,3-Trichloropropane : Technical Report', published 2006 under ISBN 9781422304198 and ISBN 1422304191.